Six Months of Diazoxide Treatment at Bedtime in Newly Diagnosed Subjects With Type 1 Diabetes Does Not Influence Parameters of β-Cell Function and Autoimmunity but Improves Glycemic Control

OBJECTIVE: Continuous β-cell rest with diazoxide preserves residual endogenous insulin production in type 1 diabetes. However, side effects have hampered therapeutic usefulness. In a double-blind study, we tested whether lower, intermittent dosing of diazoxide had beneficial effects on insulin produ...

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Detalles Bibliográficos
Autores principales: Radtke, Maria Anita, Nermoen, Ingrid, Kollind, Magnus, Skeie, Svein, Sørheim, Jan Inge, Svartberg, Johan, Hals, Ingrid, Moen, Torolf, Dørflinger, Gry Høst, Grill, Valdemar
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827514/
https://www.ncbi.nlm.nih.gov/pubmed/20028939
http://dx.doi.org/10.2337/dc09-1436

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