Cargando…

Lipotoxicity and Decreased Islet Graft Survival

OBJECTIVE: To evaluate if baseline serum lipids are associated with islet graft survival in type 1 diabetes islet transplant (ITx) recipients. RESEARCH DESIGN AND METHODS: Baseline fasting lipid profile was collected from 44 ITx recipients. Comparisons were performed between subjects below and above...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leitão, Cristiane B., Bernetti, Karina, Tharavanij, Thipaporn, Cure, Pablo, Lauriola, Vincenzo, Berggren, Per-Olof, Ricordi, Camillo, Alejandro, Rodolfo
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827526/ https://www.ncbi.nlm.nih.gov/pubmed/20009097 http://dx.doi.org/10.2337/dc09-1387

Ejemplares similares

Restoration of Hypoglycemia Awareness After Islet Transplantation
por: Leitão, Cristiane B., et al.
Publicado: (2008)

Point: Steady Progress and Current Challenges in Clinical Islet Transplantation
por: Mineo, Davide, et al.
Publicado: (2009)

Ten Years of Preserved Kidney Function After Islet Transplant Graft Failure
por: Peixoto, Eduardo, et al.
Publicado: (2016)

Markedly Decreased Blood Perfusion of Pancreatic Islets Transplanted Intraportally Into the Liver: Disruption of Islet Integrity Necessary for Islet Revascularization
por: Henriksnäs, Johanna, et al.
Publicado: (2012)

Donor Islet Endothelial Cells in Pancreatic Islet Revascularization
por: Nyqvist, Daniel, et al.
Publicado: (2011)

Prevention of Lipotoxicity in Pancreatic Islets with Gammahydroxybutyrate
por: Yung, Justin Hou Ming, et al.
Publicado: (2022)

G-CSF and Exenatide Might Be Associated with Increased Long-Term Survival of Allogeneic Pancreatic Islet Grafts
por: Zoso, Alessia, et al.
Publicado: (2016)

A New Home for Pancreatic Islet Transplants: The Bone Marrow
por: Pileggi, Antonello, et al.
Publicado: (2013)

Survival After Islet Transplantation in Subjects With Type 1 Diabetes: Twenty-Year Follow-Up
por: Lemos, Joana R.N., et al.
Publicado: (2021)

Pretransplant Immune Parameters Associate With Islet Allograft Outcome: Implications for Transplant Strategy?
por: Kenyon, Norma S., et al.
Publicado: (2009)

Screening Test on Metabolic Syndrome Using Electro Interstitial Scan Instrument
por: Norchai, Phawit, et al.
Publicado: (2020)

HLA-B Matching Prolongs Allograft Survival in Islet Cell Transplantation
por: Lemos, Joana R. N., et al.
Publicado: (2023)

The Role of Vitamin D and Omega-3 PUFAs in Islet Transplantation
por: Infante, Marco, et al.
Publicado: (2019)

Protection of Human Pancreatic Islets from Lipotoxicity by Modulation of the Translocon
por: Cassel, R., et al.
Publicado: (2016)

The Eye as a Transplantation Site to Monitor Pancreatic Islet Cell Plasticity
por: Ilegems, Erwin, et al.
Publicado: (2021)

Evaluation of the Intestinal Permeability of Rosmarinic Acid from Thunbergia laurifolia Leaf Water Extract in a Caco-2 Cell Model
por: Woottisin, Nanthakarn, et al.
Publicado: (2022)

Intraocular in vivo imaging of pancreatic islet cell physiology/pathology
por: Leibiger, Ingo B., et al.
Publicado: (2017)

The Effect of Recovery Warm-up Time Following Cold Storage on the Dynamic Glucose-stimulated Insulin Secretion of Isolated Human Islets
por: Alcazar, Oscar, et al.
Publicado: (2020)

Challenges in stem cell-derived islet replacement therapy can be overcome
por: Abdulreda, Midhat H., et al.
Publicado: (2021)

Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity
por: Brajkovic, Saška, et al.
Publicado: (2016)

Impact of GAD65 and IA2 autoantibodies on islet allograft survival
por: Lemos, Joana R. N., et al.
Publicado: (2023)

Effects of Composition of Alginate-Polyethylene Glycol Microcapsules and Transplant Site on Encapsulated Islet Graft Outcomes in Mice
por: Villa, Chiara, et al.
Publicado: (2017)

Improvement of Lipotoxicity-Induced Islet β Cellular Insulin Secretion Disorder by Osteocalcin
por: Zhang, Yafang, et al.
Publicado: (2022)

Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet
por: Molina, Judith, et al.
Publicado: (2014)

Local Dexamethasone Administration Delays Allogeneic Islet Graft Rejection in the Anterior Chamber of the Eye of Non-Human Primates
por: Tun, Sai Bo Bo, et al.
Publicado: (2022)

Influence of Vitamin D on Islet Autoimmunity and Beta-Cell Function in Type 1 Diabetes
por: Infante, Marco, et al.
Publicado: (2019)

Perilipin 2 Protects against Lipotoxicity-Induced Islet Fibrosis by Inducing Islet Stellate Cell Activation Phenotype Changes
por: Zhou, Yunting, et al.
Publicado: (2022)

Sustained heterologous gene expression in pancreatic islet organoids using adeno-associated virus serotype 8
por: Voznesenskaya, Anna, et al.
Publicado: (2023)

Evaluation of Ex-Vivo Gene Transfer of Fadd-Dn to Pancreatic Islets
por: Fenjves, Elizabeth S., et al.
Publicado: (2001)

Validation of an electrochemical sensor based on gold nanoparticles as a point-of-care test for quantitative determination of glycated hemoglobin
por: Boonprasert, Kanyarat, et al.
Publicado: (2023)

Lipotoxicity is glucose-dependent in INS-1E cells but not in human islets and MIN6 cells
por: Sargsyan, Ernest, et al.
Publicado: (2011)

Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets
por: HUANG, CHENGHU, et al.
Publicado: (2015)

Glucagon-Like Peptide 1 Attenuates Lipotoxicity-Induced Islet Dysfunction in ApoE(–/–) Mice
por: Liu, Fuqiang, et al.
Publicado: (2020)

Comment on Harlan. Islet Transplantation for Hypoglycemia Unawareness/Severe Hypoglycemia: Caveat Emptor. Diabetes Care 2016;39:1072–1074
por: Hering, Bernhard J., et al.
Publicado: (2017)

Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation
por: Miki, Atsushi, et al.
Publicado: (2018)

Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming human beta cell function
por: Rodriguez-Diaz, Rayner, et al.
Publicado: (2011)

Quantification of β-Cell Mass in Intramuscular Islet Grafts Using Radiolabeled Exendin-4
por: Espes, Daniel, et al.
Publicado: (2016)

Local release of rapamycin by microparticles delays islet rejection within the anterior chamber of the eye
por: Fan, Yanliang, et al.
Publicado: (2019)

A novel toolbox to investigate tissue spatial organization applied to the study of the islets of Langerhans
por: Tran Thi Nhu, Hoa, et al.
Publicado: (2017)

Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets
por: Ciregia, Federica, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pmgk1fh979rp0fhm0if207iftm