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The Chemokine MIP1α/CCL3 Determines Pathology in Primary RSV Infection by Regulating the Balance of T Cell Populations in the Murine Lung
BACKGROUND: CD8 T cells assist in the clearance of respiratory syncytial virus (RSV) infection from the lungs. However, disease after RSV infection is in part caused by excessive T cell activity, and a balance is therefore needed between beneficial and harmful cellular immune responses. The chemokin...
Autores principales: | Tregoning, John S., Pribul, Philippa K., Pennycook, Alasdair M. J., Hussell, Tracy, Wang, Belinda, Lukacs, Nicholas, Schwarze, Jurgen, Culley, Fiona J., Openshaw, Peter J. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827540/ https://www.ncbi.nlm.nih.gov/pubmed/20195359 http://dx.doi.org/10.1371/journal.pone.0009381 |
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