Caloric Restriction Shortens Lifespan through an Increase in Lipid Peroxidation, Inflammation and Apoptosis in the G93A Mouse, an Animal Model of ALS

Caloric restriction (CR) extends lifespan through a reduction in oxidative stress, delays the onset of morbidity and prolongs lifespan. We previously reported that long-term CR hastened clinical onset, disease progression and shortened lifespan, while transiently improving motor performance in G93A...

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Detalles Bibliográficos
Autores principales: Patel, Barkha P., Safdar, Adeel, Raha, Sandeep, Tarnopolsky, Mark A., Hamadeh, Mazen J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827549/
https://www.ncbi.nlm.nih.gov/pubmed/20195368
http://dx.doi.org/10.1371/journal.pone.0009386

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