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An Optimized Pentaplex PCR for Detecting DNA Mismatch Repair-Deficient Colorectal Cancers

PURPOSE: Microsatellite instability (MSI) is used to screen colorectal cancers (CRC) for Lynch Syndrome, and to predict outcome and response to treatment. The current technique for measuring MSI requires DNA from normal and neoplastic tissues, and fails to identify tumors with specific DNA mismatch...

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Detalles Bibliográficos
Autores principales:	Goel, Ajay, Nagasaka, Takeshi, Hamelin, Richard, Boland, C. Richard
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827558/ https://www.ncbi.nlm.nih.gov/pubmed/20195377 http://dx.doi.org/10.1371/journal.pone.0009393

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