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Impaired Ca(2+)-handling in HIF-1α(+/−) mice as a consequence of pressure overload
The hypoxia-inducible factor (HIF)-1 is critically involved in the cellular adaptation to a decrease in oxygen availability. The influence of HIF-1α for the development of cardiac hypertrophy and cardiac function that occurs in response to sustained pressure overload has been mainly attributed to a...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827795/ https://www.ncbi.nlm.nih.gov/pubmed/19898976 http://dx.doi.org/10.1007/s00424-009-0748-x |