Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS

Motivation: Epistasis, the presence of gene–gene interactions, has been hypothesized to be at the root of many common human diseases, but current genome-wide association studies largely ignore its role. Multifactor dimensionality reduction (MDR) is a powerful model-free method for detecting epistati...

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Detalles Bibliográficos
Autores principales: Greene, Casey S., Sinnott-Armstrong, Nicholas A., Himmelstein, Daniel S., Park, Paul J., Moore, Jason H., Harris, Brent T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828117/
https://www.ncbi.nlm.nih.gov/pubmed/20081222
http://dx.doi.org/10.1093/bioinformatics/btq009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828117/
https://www.ncbi.nlm.nih.gov/pubmed/20081222
http://dx.doi.org/10.1093/bioinformatics/btq009

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