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Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS
Motivation: Epistasis, the presence of gene–gene interactions, has been hypothesized to be at the root of many common human diseases, but current genome-wide association studies largely ignore its role. Multifactor dimensionality reduction (MDR) is a powerful model-free method for detecting epistati...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828117/ https://www.ncbi.nlm.nih.gov/pubmed/20081222 http://dx.doi.org/10.1093/bioinformatics/btq009 |