Senescent vs. non-senescent cells in the human annulus in vivo: Cell harvest with laser capture microdissection and gene expression studies with microarray analysis

BACKGROUND: Senescent cells are well-recognized in the aging/degenerating human disc. Senescent cells are viable, cannot divide, remain metabolically active and accumulate within the disc over time. Molecular analysis of senescent cells in tissue offers a special challenge since there are no cell su...

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Detalles Bibliográficos
Autores principales: Gruber, Helen E, Hoelscher, Gretchen L, Ingram, Jane A, Zinchenko, Natalia, Hanley, Edward N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828399/
https://www.ncbi.nlm.nih.gov/pubmed/20109216
http://dx.doi.org/10.1186/1472-6750-10-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828399/
https://www.ncbi.nlm.nih.gov/pubmed/20109216
http://dx.doi.org/10.1186/1472-6750-10-5

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