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Activated Ras alters lens and corneal development through induction of distinct downstream targets
BACKGROUND: Mammalian Ras genes regulate diverse cellular processes including proliferation and differentiation and are frequently mutated in human cancers. Tumor development in response to Ras activation varies between different tissues and the molecular basis for these variations are poorly unders...
Autores principales: | Burgess, Daniel, Zhang, Yan, Siefker, Ed, Vaca, Ryan, Kuracha, Murali R, Reneker, Lixing, Overbeek, Paul A, Govindarajan, Venkatesh |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828409/ https://www.ncbi.nlm.nih.gov/pubmed/20105280 http://dx.doi.org/10.1186/1471-213X-10-13 |
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