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Crystal structure of the signaling helix coiled-coil domain of the β1 subunit of the soluble guanylyl cyclase
BACKGROUND: The soluble guanylyl cyclase (sGC) is a heterodimeric enzyme that, upon activation by nitric oxide, stimulates the production of the second messenger cGMP. Each sGC subunit harbor four domains three of which are used for heterodimerization: H-NOXA/H-NOBA domain, coiled-coil domain (CC),...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828450/ https://www.ncbi.nlm.nih.gov/pubmed/20105301 http://dx.doi.org/10.1186/1472-6807-10-2 |