Crystal structure of the signaling helix coiled-coil domain of the β1 subunit of the soluble guanylyl cyclase

BACKGROUND: The soluble guanylyl cyclase (sGC) is a heterodimeric enzyme that, upon activation by nitric oxide, stimulates the production of the second messenger cGMP. Each sGC subunit harbor four domains three of which are used for heterodimerization: H-NOXA/H-NOBA domain, coiled-coil domain (CC),...

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Detalles Bibliográficos
Autores principales: Ma, Xiaolei, Beuve, Annie, van den Akker, Focco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828450/
https://www.ncbi.nlm.nih.gov/pubmed/20105301
http://dx.doi.org/10.1186/1472-6807-10-2

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