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The Core Binding Factor CBF Negatively Regulates Skeletal Muscle Terminal Differentiation

BACKGROUND: Core Binding Factor or CBF is a transcription factor composed of two subunits, Runx1/AML-1 and CBF beta or CBFβ. CBF was originally described as a regulator of hematopoiesis. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that CBF is involved in the control of skeletal muscle terminal diff...

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Detalles Bibliográficos
Autores principales: Philipot, Ophélie, Joliot, Véronique, Ait-Mohamed, Ouardia, Pellentz, Céline, Robin, Philippe, Fritsch, Lauriane, Ait-Si-Ali, Slimane
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828485/
https://www.ncbi.nlm.nih.gov/pubmed/20195544
http://dx.doi.org/10.1371/journal.pone.0009425