Cargando…
Insulin-Sensitizing Therapy Attenuates Type 2 Diabetes–Mediated Mammary Tumor Progression
OBJECTIVE: Type 2 diabetes increases breast cancer risk and mortality, and hyperinsulinemia has been identified as a major factor linking these two diseases. Thus, we hypothesized that pharmacological reduction of elevated insulin levels would attenuate type 2 diabetes–mediated mammary tumor progres...
Autores principales: | Fierz, Yvonne, Novosyadlyy, Ruslan, Vijayakumar, Archana, Yakar, Shoshana, LeRoith, Derek |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828655/ https://www.ncbi.nlm.nih.gov/pubmed/19959755 http://dx.doi.org/10.2337/db09-1291 |
Ejemplares similares
-
Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes
por: Ferguson, Rosalyn D, et al.
Publicado: (2012) -
Inhibiting PI3K reduces mammary tumor growth and induces hyperglycemia in a mouse model of insulin resistance and hyperinsulinemia
por: Gallagher, Emily Jane, et al.
Publicado: (2011) -
The Intricate Role of Growth Hormone in Metabolism
por: Vijayakumar, Archana, et al.
Publicado: (2011) -
Physical and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiation
por: Novosyadlyy, R, et al.
Publicado: (2009) -
Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor Growth
por: Ben-Shmuel, Sarit, et al.
Publicado: (2017)