Detailed Investigation of the Role of Common and Low-Frequency WFS1 Variants in Type 2 Diabetes Risk

OBJECTIVE: Wolfram syndrome 1 (WFS1) single nucleotide polymorphisms (SNPs) are associated with risk of type 2 diabetes. In this study we aimed to refine this association and investigate the role of low-frequency WFS1 variants in type 2 diabetes risk. RESEARCH DESIGN AND METHODS: For fine-mapping, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Fawcett, Katherine A., Wheeler, Eleanor, Morris, Andrew P., Ricketts, Sally L., Hallmans, Göran, Rolandsson, Olov, Daly, Allan, Wasson, Jon, Permutt, Alan, Hattersley, Andrew T., Glaser, Benjamin, Franks, Paul W., McCarthy, Mark I., Wareham, Nicholas J., Sandhu, Manjinder S., Barroso, Inês
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828659/
https://www.ncbi.nlm.nih.gov/pubmed/20028947
http://dx.doi.org/10.2337/db09-0920

Ejemplares similares

Ejemplares similares