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Progression to Diabetes in Relatives of Type 1 Diabetic Patients: Mechanisms and Mode of Onset

OBJECTIVE: Relatives of type 1 diabetic patients are at enhanced risk of developing diabetes. We investigated the mode of onset of hyperglycemia and how insulin sensitivity and β-cell function contribute to the progression to the disease. RESEARCH DESIGN AND METHODS: In 328 islet cell autoantibody–p...

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Detalles Bibliográficos
Autores principales: Ferrannini, Ele, Mari, Andrea, Nofrate, Valentina, Sosenko, Jay M., Skyler, Jay S.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828663/
https://www.ncbi.nlm.nih.gov/pubmed/20028949
http://dx.doi.org/10.2337/db09-1378