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Gene Variants of TCF7L2 Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes

OBJECTIVE: The impact of the diabetes risk gene transcription factor 7-like 2 (TCF7L2) on body weight is unclear. As TCF7L2 is expressed in adipose tissue and involved in Wnt-dependent regulation of adipogenesis, we studied the impact of TCF7L2 variants on body composition and weight loss during lif...

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Detalles Bibliográficos
Autores principales:	Haupt, Axel, Thamer, Claus, Heni, Martin, Ketterer, Caroline, Machann, Jürgen, Schick, Fritz, Machicao, Fausto, Stefan, Norbert, Claussen, Claus D., Häring, Hans-Ulrich, Fritsche, Andreas, Staiger, Harald
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828665/ https://www.ncbi.nlm.nih.gov/pubmed/20028944 http://dx.doi.org/10.2337/db09-1050

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