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Allelic imbalance sequencing reveals that single-nucleotide polymorphisms frequently alter microRNA-directed repression
Genetic changes that help explain the differences between two individuals might include those that create or disrupt sites complementary to microRNAs1,2, but the extent to which such polymorphic microRNA sites mediate repression is unknown. Here, we develop a method to measure mRNA allelic imbalance...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828817/ https://www.ncbi.nlm.nih.gov/pubmed/19396161 http://dx.doi.org/10.1038/nbt.1540 |