Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

VEGF can be secreted in multiple isoforms with variable affinity for extracellular proteins and different abilities to induce vascular morphogenesis, but the molecular mechanisms behind these effects remain unclear. Here, we show molecular distinctions between signaling initiated from soluble versus...

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Detalles Bibliográficos
Autores principales: Chen, Tom T., Luque, Alfonso, Lee, Sunyoung, Anderson, Sean M., Segura, Tatiana, Iruela-Arispe, M. Luisa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828913/
https://www.ncbi.nlm.nih.gov/pubmed/20176926
http://dx.doi.org/10.1083/jcb.200906044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828913/
https://www.ncbi.nlm.nih.gov/pubmed/20176926
http://dx.doi.org/10.1083/jcb.200906044

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