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Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells
VEGF can be secreted in multiple isoforms with variable affinity for extracellular proteins and different abilities to induce vascular morphogenesis, but the molecular mechanisms behind these effects remain unclear. Here, we show molecular distinctions between signaling initiated from soluble versus...
Autores principales: | Chen, Tom T., Luque, Alfonso, Lee, Sunyoung, Anderson, Sean M., Segura, Tatiana, Iruela-Arispe, M. Luisa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828913/ https://www.ncbi.nlm.nih.gov/pubmed/20176926 http://dx.doi.org/10.1083/jcb.200906044 |
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