Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein

Protein translocation into the endoplasmic reticulum is mediated by signal sequences that vary widely in primary structure. In vitro studies suggest that such signal sequence variations may correspond to subtly different functional properties. Whether comparable functional differences exist in vivo...

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Detalles Bibliográficos
Autores principales: Rane, Neena S., Chakrabarti, Oishee, Feigenbaum, Lionel, Hegde, Ramanujan S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828915/
https://www.ncbi.nlm.nih.gov/pubmed/20156965
http://dx.doi.org/10.1083/jcb.200911115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828915/
https://www.ncbi.nlm.nih.gov/pubmed/20156965
http://dx.doi.org/10.1083/jcb.200911115

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