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Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells

In an RNA interference screen interrogating regulators of mouse embryonic stem (ES) cell chromatin structure, we previously identified 62 genes required for ES cell viability. Among these 62 genes were Smc2 and -4, which are core components of the two mammalian condensin complexes. In this study, we...

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Detalles Bibliográficos
Autores principales: Fazzio, Thomas G., Panning, Barbara
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828918/
https://www.ncbi.nlm.nih.gov/pubmed/20176923
http://dx.doi.org/10.1083/jcb.200908026