BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity

Mutations in the gene coding for DJ-1 protein lead to early-onset recessive forms of Parkinson’s disease. It is believed that loss of DJ-1 function is causative for disease, although the function of DJ-1 still remains a matter of controversy. We show that DJ-1 is localized in the cytosol and is asso...

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Detalles Bibliográficos
Autores principales: Deeg, Sebastian, Gralle, Mathias, Sroka, Kamila, Bähr, Mathias, Wouters, Fred Silvester, Kermer, Pawel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828921/
https://www.ncbi.nlm.nih.gov/pubmed/20156966
http://dx.doi.org/10.1083/jcb.200904103

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