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Reduced blood brain barrier breakdown in P-selectin deficient mice following transient ischemic stroke: a future therapeutic target for treatment of stroke

BACKGROUND: The link between early blood- brain barrier (BBB) breakdown and endothelial cell activation in acute stroke remain poorly defined. We hypothesized that P-selectin, a mediator of the early phase of leukocyte recruitment in acute ischemia is also a major contributor to early BBB dysfunctio...

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Detalles Bibliográficos
Autores principales:	Jin, Albert Y, Tuor, Ursula I, Rushforth, David, Kaur, Jaspreet, Muller, Robert N, Petterson, Jodie Lee, Boutry, Sébastien, Barber, Philip A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829030/ https://www.ncbi.nlm.nih.gov/pubmed/20122276 http://dx.doi.org/10.1186/1471-2202-11-12

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