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Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells

The repair of DNA double-strand breaks (DSBs) is critical for the maintenance of genomic integrity and viability for all organisms. Mammals have evolved at least two genetically discrete ways to mediate DNA DSB repair: homologous recombination (HR) and non-homologous end joining (NHEJ). In mammalian...

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Detalles Bibliográficos
Autores principales:	Fattah, Farjana, Lee, Eu Han, Weisensel, Natalie, Wang, Yongbao, Lichter, Natalie, Hendrickson, Eric A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829059/ https://www.ncbi.nlm.nih.gov/pubmed/20195511 http://dx.doi.org/10.1371/journal.pgen.1000855

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