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Cdk1 Targets Srs2 to Complete Synthesis-Dependent Strand Annealing and to Promote Recombinational Repair

Cdk1 kinase phosphorylates budding yeast Srs2, a member of UvrD protein family, displays both DNA translocation and DNA unwinding activities in vitro. Srs2 prevents homologous recombination by dismantling Rad51 filaments and is also required for double-strand break (DSB) repair. Here we examine the...

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Detalles Bibliográficos
Autores principales:	Saponaro, Marco, Callahan, Devon, Zheng, Xiuzhong, Krejci, Lumir, Haber, James E., Klein, Hannah L., Liberi, Giordano
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829061/ https://www.ncbi.nlm.nih.gov/pubmed/20195513 http://dx.doi.org/10.1371/journal.pgen.1000858

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