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A Tyrosine Residue on the TSH Receptor Stabilizes Multimer Formation

BACKGROUND: The thyrotropin stimulating hormone receptor (TSHR) is a G protein coupled receptor (GPCR) with a large ectodomain. The ligand, TSH, acting via this receptor regulates thyroid growth and thyroid hormone production and secretion. The TSH receptor (TSHR) undergoes complex post –translation...

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Detalles Bibliográficos
Autores principales: Latif, Rauf, Michalek, Krzysztof, Morshed, Syed Ahmed, Davies, Terry F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829087/
https://www.ncbi.nlm.nih.gov/pubmed/20195479
http://dx.doi.org/10.1371/journal.pone.0009449