Differential Epidermal Growth Factor Receptor Signaling Regulates Anchorage-Independent Growth by Modulation of the PI3K/AKT Pathway

Tumor cells are capable of surviving loss of nutrients and anchorage in hostile microenvironments. Under these conditions adapting to specific signaling pathways may shift the balance between growth and cellular dormancy. Here we report a mechanism by which EGFR differentially modulates the PI3K/AKT...

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Detalles Bibliográficos
Autores principales: Humtsoe, Joseph O., Kramer, Randall H.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829113/
https://www.ncbi.nlm.nih.gov/pubmed/19935697
http://dx.doi.org/10.1038/onc.2009.419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829113/
https://www.ncbi.nlm.nih.gov/pubmed/19935697
http://dx.doi.org/10.1038/onc.2009.419

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