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Intracellular Ca(2+ )regulating proteins in vascular smooth muscle cells are altered with type 1 diabetes due to the direct effects of hyperglycemia

BACKGROUND: Diminished calcium (Ca(2+)) transients in response to physiological agonists have been reported in vascular smooth muscle cells (VSMCs) from diabetic animals. However, the mechanism responsible was unclear. METHODOLOGY/PRINCIPAL FINDINGS: VSMCs from autoimmune type 1 Diabetes Resistant B...

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Detalles Bibliográficos
Autores principales: Searls, Yvonne M, Loganathan, Rajprasad, Smirnova, Irina V, Stehno-Bittel, Lisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829469/
https://www.ncbi.nlm.nih.gov/pubmed/20122173
http://dx.doi.org/10.1186/1475-2840-9-8