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Intracellular Ca(2+ )regulating proteins in vascular smooth muscle cells are altered with type 1 diabetes due to the direct effects of hyperglycemia
BACKGROUND: Diminished calcium (Ca(2+)) transients in response to physiological agonists have been reported in vascular smooth muscle cells (VSMCs) from diabetic animals. However, the mechanism responsible was unclear. METHODOLOGY/PRINCIPAL FINDINGS: VSMCs from autoimmune type 1 Diabetes Resistant B...
Autores principales: | Searls, Yvonne M, Loganathan, Rajprasad, Smirnova, Irina V, Stehno-Bittel, Lisa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829469/ https://www.ncbi.nlm.nih.gov/pubmed/20122173 http://dx.doi.org/10.1186/1475-2840-9-8 |
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