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Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole

BACKGROUND: Pramipexole exists as two isomers. The S(-) enantiomer is a potent D(3)/D(2 )receptor agonist and is extensively used in the management of PD. In contrast, the R(+) enantiomer is virtually devoid of any of the DA agonist effects. Very limited studies are available to characterize the pha...

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Detalles Bibliográficos
Autores principales: Ferrari-Toninelli, Giulia, Maccarinelli, Giuseppina, Uberti, Daniela, Buerger, Erich, Memo, Maurizio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829550/
https://www.ncbi.nlm.nih.gov/pubmed/20137065
http://dx.doi.org/10.1186/1471-2210-10-2