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Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole
BACKGROUND: Pramipexole exists as two isomers. The S(-) enantiomer is a potent D(3)/D(2 )receptor agonist and is extensively used in the management of PD. In contrast, the R(+) enantiomer is virtually devoid of any of the DA agonist effects. Very limited studies are available to characterize the pha...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829550/ https://www.ncbi.nlm.nih.gov/pubmed/20137065 http://dx.doi.org/10.1186/1471-2210-10-2 |