High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome

BACKGROUND: Neurotoxicity is a recognized complication of cyclosporine A (CSA) treatment. The incidence of severe CSA-related neurological complications following hematopoietic stem cell transplantation (HSCT) is 4-11%. METHODS: We describe 6 cases of CSA related neurotoxicity out of 67 matched rela...

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Detalles Bibliográficos
Autores principales: Noè, Anna, Cappelli, Barbara, Biffi, Alessandra, Chiesa, Robert, Frugnoli, Ilaria, Biral, Erika, Finizio, Valentina, Baldoli, Cristina, Vezzulli, Paolo, Minicucci, Fabio, Fanelli, Giovanna, Fiori, Rossana, Ciceri, Fabio, Roncarolo, Maria Grazia, Marktel, Sarah
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829572/
https://www.ncbi.nlm.nih.gov/pubmed/20181110
http://dx.doi.org/10.1186/1824-7288-36-14

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