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IL-1β Suppresses the Formation of Osteoclasts by Increasing OPG Production via an Autocrine Mechanism Involving Celecoxib-Related Prostaglandins in Chondrocytes

Elevated interleukin (IL)-1 concentrations in synovial fluid have been implicated in joint bone and cartilage destruction. Previously, we showed that IL-1β stimulated the expression of prostaglandin (PG) receptor EP4 via increased PGE(2) production. However, the effect of IL-1β on osteoclast formati...

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Detalles Bibliográficos
Autores principales:	Watanabe, Yusuke, Namba, Aki, Aida, Yukiko, Honda, Kazuhiro, Tanaka, Hideki, Suzuki, Naoto, Matsumura, Hideo, Maeno, Masao
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829618/ https://www.ncbi.nlm.nih.gov/pubmed/20204061 http://dx.doi.org/10.1155/2009/308596

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