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A simple algebraic cancer equation: calculating how cancers may arise with normal mutation rates
BACKGROUND: The purpose of this article is to present a relatively easy to understand cancer model where transformation occurs when the first cell, among many at risk within a colon, accumulates a set of driver mutations. The analysis of this model yields a simple algebraic equation, which takes as...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829925/ https://www.ncbi.nlm.nih.gov/pubmed/20051132 http://dx.doi.org/10.1186/1471-2407-10-3 |