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A simple algebraic cancer equation: calculating how cancers may arise with normal mutation rates

BACKGROUND: The purpose of this article is to present a relatively easy to understand cancer model where transformation occurs when the first cell, among many at risk within a colon, accumulates a set of driver mutations. The analysis of this model yields a simple algebraic equation, which takes as...

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Detalles Bibliográficos
Autores principales: Calabrese, Peter, Shibata, Darryl
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829925/
https://www.ncbi.nlm.nih.gov/pubmed/20051132
http://dx.doi.org/10.1186/1471-2407-10-3

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