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Magnetically Remote-Controlled Optical Sensor Spheres for Monitoring Oxygen or pH

Magnetic sensor macrospheres (MagSeMacs), i.e., stainless steel spheres coated with optical chemical sensors, are presented as an alternative to existing optical sensor patches and fiber-optical dip-probes. Such spheres can either be reversibly attached to the tip of an optical fiber (dip-probe) or...

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Autores principales: Mistlberger, Günter, Koren, Klaus, Borisov, Sergey M., Klimant, Ingo
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829951/
https://www.ncbi.nlm.nih.gov/pubmed/20121206
http://dx.doi.org/10.1021/ac902393u
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author Mistlberger, Günter
Koren, Klaus
Borisov, Sergey M.
Klimant, Ingo
author_facet Mistlberger, Günter
Koren, Klaus
Borisov, Sergey M.
Klimant, Ingo
author_sort Mistlberger, Günter
collection PubMed
description Magnetic sensor macrospheres (MagSeMacs), i.e., stainless steel spheres coated with optical chemical sensors, are presented as an alternative to existing optical sensor patches and fiber-optical dip-probes. Such spheres can either be reversibly attached to the tip of an optical fiber (dip-probe) or trapped inside a vessel for read-out through the side wall. Moving the magnetic separator at the exterior enables measurements at varying positions with a single sensor. Moreover, the sensor’s replacement is rapid and contactless. We measured dissolved oxygen or pH in stirred liquids, rotating flasks, and 24-well plates with a SensorDish-reader device for parallel cell culture monitoring. In these applications, MagSeMacs proved to be advantageous over conventional sensor patches and magnetic optical sensor particles because of their magnetism, spherical shape, reflectance, and size. These properties resulted in strong but reversible fixation, magnetic remote-controllability, short response times, high signal intensities, and simplified handling.
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spelling pubmed-28299512010-03-01 Magnetically Remote-Controlled Optical Sensor Spheres for Monitoring Oxygen or pH Mistlberger, Günter Koren, Klaus Borisov, Sergey M. Klimant, Ingo Anal Chem Magnetic sensor macrospheres (MagSeMacs), i.e., stainless steel spheres coated with optical chemical sensors, are presented as an alternative to existing optical sensor patches and fiber-optical dip-probes. Such spheres can either be reversibly attached to the tip of an optical fiber (dip-probe) or trapped inside a vessel for read-out through the side wall. Moving the magnetic separator at the exterior enables measurements at varying positions with a single sensor. Moreover, the sensor’s replacement is rapid and contactless. We measured dissolved oxygen or pH in stirred liquids, rotating flasks, and 24-well plates with a SensorDish-reader device for parallel cell culture monitoring. In these applications, MagSeMacs proved to be advantageous over conventional sensor patches and magnetic optical sensor particles because of their magnetism, spherical shape, reflectance, and size. These properties resulted in strong but reversible fixation, magnetic remote-controllability, short response times, high signal intensities, and simplified handling. American Chemical Society 2010-02-02 2010-03-01 /pmc/articles/PMC2829951/ /pubmed/20121206 http://dx.doi.org/10.1021/ac902393u Text en Copyright © 2010 American Chemical Society http://pubs.acs.org This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org.
spellingShingle Mistlberger, Günter
Koren, Klaus
Borisov, Sergey M.
Klimant, Ingo
Magnetically Remote-Controlled Optical Sensor Spheres for Monitoring Oxygen or pH
title Magnetically Remote-Controlled Optical Sensor Spheres for Monitoring Oxygen or pH
title_full Magnetically Remote-Controlled Optical Sensor Spheres for Monitoring Oxygen or pH
title_fullStr Magnetically Remote-Controlled Optical Sensor Spheres for Monitoring Oxygen or pH
title_full_unstemmed Magnetically Remote-Controlled Optical Sensor Spheres for Monitoring Oxygen or pH
title_short Magnetically Remote-Controlled Optical Sensor Spheres for Monitoring Oxygen or pH
title_sort magnetically remote-controlled optical sensor spheres for monitoring oxygen or ph
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829951/
https://www.ncbi.nlm.nih.gov/pubmed/20121206
http://dx.doi.org/10.1021/ac902393u
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