Cargando…
Lasers, stem cells, and COPD
The medical use of low level laser (LLL) irradiation has been occurring for decades, primarily in the area of tissue healing and inflammatory conditions. Despite little mechanistic knowledge, the concept of a non-invasive, non-thermal intervention that has the potential to modulate regenerative proc...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830167/ https://www.ncbi.nlm.nih.gov/pubmed/20158898 http://dx.doi.org/10.1186/1479-5876-8-16 |
_version_ | 1782178142879744000 |
---|---|
author | Lin, Feng Josephs, Steven F Alexandrescu, Doru T Ramos, Famela Bogin, Vladimir Gammill, Vincent Dasanu, Constantin A De Necochea-Campion, Rosalia Patel, Amit N Carrier, Ewa Koos, David R |
author_facet | Lin, Feng Josephs, Steven F Alexandrescu, Doru T Ramos, Famela Bogin, Vladimir Gammill, Vincent Dasanu, Constantin A De Necochea-Campion, Rosalia Patel, Amit N Carrier, Ewa Koos, David R |
author_sort | Lin, Feng |
collection | PubMed |
description | The medical use of low level laser (LLL) irradiation has been occurring for decades, primarily in the area of tissue healing and inflammatory conditions. Despite little mechanistic knowledge, the concept of a non-invasive, non-thermal intervention that has the potential to modulate regenerative processes is worthy of attention when searching for novel methods of augmenting stem cell-based therapies. Here we discuss the use of LLL irradiation as a "photoceutical" for enhancing production of stem cell growth/chemoattractant factors, stimulation of angiogenesis, and directly augmenting proliferation of stem cells. The combination of LLL together with allogeneic and autologous stem cells, as well as post-mobilization directing of stem cells will be discussed. |
format | Text |
id | pubmed-2830167 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-28301672010-03-02 Lasers, stem cells, and COPD Lin, Feng Josephs, Steven F Alexandrescu, Doru T Ramos, Famela Bogin, Vladimir Gammill, Vincent Dasanu, Constantin A De Necochea-Campion, Rosalia Patel, Amit N Carrier, Ewa Koos, David R J Transl Med Review The medical use of low level laser (LLL) irradiation has been occurring for decades, primarily in the area of tissue healing and inflammatory conditions. Despite little mechanistic knowledge, the concept of a non-invasive, non-thermal intervention that has the potential to modulate regenerative processes is worthy of attention when searching for novel methods of augmenting stem cell-based therapies. Here we discuss the use of LLL irradiation as a "photoceutical" for enhancing production of stem cell growth/chemoattractant factors, stimulation of angiogenesis, and directly augmenting proliferation of stem cells. The combination of LLL together with allogeneic and autologous stem cells, as well as post-mobilization directing of stem cells will be discussed. BioMed Central 2010-02-16 /pmc/articles/PMC2830167/ /pubmed/20158898 http://dx.doi.org/10.1186/1479-5876-8-16 Text en Copyright ©2010 Lin et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Lin, Feng Josephs, Steven F Alexandrescu, Doru T Ramos, Famela Bogin, Vladimir Gammill, Vincent Dasanu, Constantin A De Necochea-Campion, Rosalia Patel, Amit N Carrier, Ewa Koos, David R Lasers, stem cells, and COPD |
title | Lasers, stem cells, and COPD |
title_full | Lasers, stem cells, and COPD |
title_fullStr | Lasers, stem cells, and COPD |
title_full_unstemmed | Lasers, stem cells, and COPD |
title_short | Lasers, stem cells, and COPD |
title_sort | lasers, stem cells, and copd |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830167/ https://www.ncbi.nlm.nih.gov/pubmed/20158898 http://dx.doi.org/10.1186/1479-5876-8-16 |
work_keys_str_mv | AT linfeng lasersstemcellsandcopd AT josephsstevenf lasersstemcellsandcopd AT alexandrescudorut lasersstemcellsandcopd AT ramosfamela lasersstemcellsandcopd AT boginvladimir lasersstemcellsandcopd AT gammillvincent lasersstemcellsandcopd AT dasanuconstantina lasersstemcellsandcopd AT denecocheacampionrosalia lasersstemcellsandcopd AT patelamitn lasersstemcellsandcopd AT carrierewa lasersstemcellsandcopd AT koosdavidr lasersstemcellsandcopd |