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Targeting lentiviral vector to specific cell types through surface displayed single chain antibody and fusogenic molecule
BACKGROUND: Viral delivery remains one of the most commonly used techniques today in the field of gene therapy. However, one of the remaining hurdles is the off-targeting effect of viral delivery. To overcome this obstacle, we recently developed a method to incorporate an antibody and a fusogenic mo...
Autores principales: | Lei, Yuning, Joo, Kye-Il, Zarzar, Jonathan, Wong, Clement, Wang, Pin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830192/ https://www.ncbi.nlm.nih.gov/pubmed/20149250 http://dx.doi.org/10.1186/1743-422X-7-35 |
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