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Transcription-dependent silencing of inducible convergent transgenes in transgenic mice
BACKGROUND: Silencing of transgenes in mice is a common phenomenon typically associated with short multi-copy transgenes. We have investigated the regulation of the highly inducible human granulocyte-macrophage colony-stimulating-factor gene (Csf2) in transgenic mice. RESULTS: In the absence of any...
Autores principales: | Calero-Nieto, Fernando J, Bert, Andrew G, Cockerill, Peter N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830199/ https://www.ncbi.nlm.nih.gov/pubmed/20180972 http://dx.doi.org/10.1186/1756-8935-3-3 |
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