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Dynamic transport and localization of alpha-synuclein in primary hippocampal neurons

BACKGROUND: Alpha-synuclein is a presynaptic protein with a proposed role in neurotransmission and dopamine homeostasis. Abnormal accumulation of α-synuclein aggregates in dopaminergic neurons of the substantia nigra is diagnostic of sporadic Parkinson's disease, and mutations in the protein ar...

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Detalles Bibliográficos
Autores principales:	Yang, Mong-Lin, Hasadsri, Linda, Woods, Wendy S, George, Julia M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830200/ https://www.ncbi.nlm.nih.gov/pubmed/20181133 http://dx.doi.org/10.1186/1750-1326-5-9

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