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Immune Modulation by Schistosoma mansoni Antigens in NOD Mice: Effects on Both Innate and Adaptive Immune Systems
We have shown that Schistosoma mansoni egg soluble antigen (SEA) prevents diabetes in the nonobese diabetic (NOD) mouse inducing functional changes in antigen presenting cells (APCs) and expanding T helper (Th) 2 and regulatory T cell (Treg) responses. A Th2 response to S. mansoni infection or its a...
Autores principales: | Zaccone, Paola, Burton, Oliver T., Gibbs, Sarah, Miller, Nigel, Jones, Frances M., Dunne, David W., Cooke, Anne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830582/ https://www.ncbi.nlm.nih.gov/pubmed/20204176 http://dx.doi.org/10.1155/2010/795210 |
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