Non-consensus GLI binding sites in Hedgehog target gene regulation

BACKGROUND: The GLI transcription factors, mediators of the hedgehog signal bind with high affinity to the consensus sequence GACCACCCA. The affinity of variant single substitutions in GLI binding sites has been measured systematically, but the affinities of the variant binding sites appears low com...

Descripción completa

Detalles Bibliográficos
Autores principales: Winklmayr, Martina, Schmid, Carmen, Laner-Plamberger, Sandra, Kaser, Alexandra, Aberger, Fritz, Eichberger, Thomas, Frischauf, Anna-Maria
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830928/
https://www.ncbi.nlm.nih.gov/pubmed/20070907
http://dx.doi.org/10.1186/1471-2199-11-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830928/
https://www.ncbi.nlm.nih.gov/pubmed/20070907
http://dx.doi.org/10.1186/1471-2199-11-2

Ejemplares similares