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R-Ras regulates β(1)-integrin trafficking via effects on membrane ruffling and endocytosis

BACKGROUND: Integrin-mediated cell adhesion and spreading is dramatically enhanced by activation of the small GTPase, R-Ras. Moreover, R-Ras localizes to the leading edge of migrating cells, and regulates membrane protrusion. The exact mechanisms by which R-Ras regulates integrin function are not fu...

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Detalles Bibliográficos
Autores principales:	Conklin, Matthew W, Ada-Nguema, Aude, Parsons, Maddy, Riching, Kristin M, Keely, Patricia J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830936/ https://www.ncbi.nlm.nih.gov/pubmed/20167113 http://dx.doi.org/10.1186/1471-2121-11-14

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