Cargando…

Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination

The current pandemic influenza A H1N1 2009 (pH1N1) was first recognized in humans with acute respiratory diseases in April 2009 in Mexico, in swine in Canada in June, 2009 with respiratory disease, and in turkeys in Chile in June 2009 with a severe drop in egg production. Several experimental studie...

Descripción completa

Detalles Bibliográficos
Autores principales: Pantin-Jackwood, Mary, Wasilenko, Jamie L, Spackman, Erica, Suarez, David L, Swayne, David E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830961/
https://www.ncbi.nlm.nih.gov/pubmed/20128914
http://dx.doi.org/10.1186/1743-422X-7-27
_version_ 1782178190506065920
author Pantin-Jackwood, Mary
Wasilenko, Jamie L
Spackman, Erica
Suarez, David L
Swayne, David E
author_facet Pantin-Jackwood, Mary
Wasilenko, Jamie L
Spackman, Erica
Suarez, David L
Swayne, David E
author_sort Pantin-Jackwood, Mary
collection PubMed
description The current pandemic influenza A H1N1 2009 (pH1N1) was first recognized in humans with acute respiratory diseases in April 2009 in Mexico, in swine in Canada in June, 2009 with respiratory disease, and in turkeys in Chile in June 2009 with a severe drop in egg production. Several experimental studies attempted to reproduce the disease in turkeys, but failed to produce respiratory infection in turkeys using standard inoculation routes. We demonstrated that pH1N1 virus can infect the reproductive tract of turkey hens after experimental intrauterine inoculation, causing decreased egg production. This route of exposure is realistic in modern turkey production because turkey hens are handled once a week for intrauterine insemination in order to produce fertile eggs. This understanding of virus exposure provides an improved understanding of the pathogenesis of the disease and can improve poultry husbandry to prevent disease outbreaks.
format Text
id pubmed-2830961
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-28309612010-03-03 Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination Pantin-Jackwood, Mary Wasilenko, Jamie L Spackman, Erica Suarez, David L Swayne, David E Virol J Short Report The current pandemic influenza A H1N1 2009 (pH1N1) was first recognized in humans with acute respiratory diseases in April 2009 in Mexico, in swine in Canada in June, 2009 with respiratory disease, and in turkeys in Chile in June 2009 with a severe drop in egg production. Several experimental studies attempted to reproduce the disease in turkeys, but failed to produce respiratory infection in turkeys using standard inoculation routes. We demonstrated that pH1N1 virus can infect the reproductive tract of turkey hens after experimental intrauterine inoculation, causing decreased egg production. This route of exposure is realistic in modern turkey production because turkey hens are handled once a week for intrauterine insemination in order to produce fertile eggs. This understanding of virus exposure provides an improved understanding of the pathogenesis of the disease and can improve poultry husbandry to prevent disease outbreaks. BioMed Central 2010-02-03 /pmc/articles/PMC2830961/ /pubmed/20128914 http://dx.doi.org/10.1186/1743-422X-7-27 Text en Copyright ©2010 Pantin-Jackwood et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Pantin-Jackwood, Mary
Wasilenko, Jamie L
Spackman, Erica
Suarez, David L
Swayne, David E
Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination
title Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination
title_full Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination
title_fullStr Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination
title_full_unstemmed Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination
title_short Susceptibility of turkeys to pandemic-H1N1 virus by reproductive tract insemination
title_sort susceptibility of turkeys to pandemic-h1n1 virus by reproductive tract insemination
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830961/
https://www.ncbi.nlm.nih.gov/pubmed/20128914
http://dx.doi.org/10.1186/1743-422X-7-27
work_keys_str_mv AT pantinjackwoodmary susceptibilityofturkeystopandemich1n1virusbyreproductivetractinsemination
AT wasilenkojamiel susceptibilityofturkeystopandemich1n1virusbyreproductivetractinsemination
AT spackmanerica susceptibilityofturkeystopandemich1n1virusbyreproductivetractinsemination
AT suarezdavidl susceptibilityofturkeystopandemich1n1virusbyreproductivetractinsemination
AT swaynedavide susceptibilityofturkeystopandemich1n1virusbyreproductivetractinsemination