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Vpu-dependent block to incorporation of GaLV Env into lentiviral vectors
BACKGROUND: The gibbon ape leukemia virus (GaLV) Env protein mediates entry into a wide range of human cells and is frequently used to pseudotype retroviral vectors. However, an incompatibility exists between GaLV Env and lentiviral vectors that results in decreased steady-state levels of the mature...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831008/ https://www.ncbi.nlm.nih.gov/pubmed/20102634 http://dx.doi.org/10.1186/1742-4690-7-4 |