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The Prognostic Value of BRCA1 mRNA Expression Levels Following Neoadjuvant Chemotherapy in Breast Cancer

BACKGROUND: A fraction of sporadic breast cancers has low BRCA1 expression. BRCA1 mutation carriers are more likely to achieve a pathological complete response with DNA-damage-based chemotherapy compared to non-mutation carriers. Furthermore, sporadic ovarian cancer patients with low levels of BRCA1...

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Detalles Bibliográficos
Autores principales: Margeli, Mireia, Cirauqui, Beatriz, Castella, Eva, Tapia, Gustavo, Costa, Carlota, Gimenez-Capitan, Ana, Barnadas, Agusti, Ronco, Maria Sanchez, Benlloch, Susana, Taron, Miquel, Rosell, Rafael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831058/
https://www.ncbi.nlm.nih.gov/pubmed/20209131
http://dx.doi.org/10.1371/journal.pone.0009499

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