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Homeostatic Imbalance of Purine Catabolism in First-Episode Neuroleptic-Naïve Patients with Schizophrenia

BACKGROUND: Purine catabolism may be an unappreciated, but important component of the homeostatic response of mitochondria to oxidant stress. Accumulating evidence suggests a pivotal role of oxidative stress in schizophrenia pathology. METHODOLOGY/PRINCIPAL FINDINGS: Using high-pressure liquid chrom...

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Detalles Bibliográficos
Autores principales:	Yao, Jeffrey K., Dougherty, George G., Reddy, Ravinder D., Keshavan, Matcheri S., Montrose, Debra M., Matson, Wayne R., McEvoy, Joseph, Kaddurah-Daouk, Rima
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831068/ https://www.ncbi.nlm.nih.gov/pubmed/20209081 http://dx.doi.org/10.1371/journal.pone.0009508

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