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Genetic Variability in CLU and Its Association with Alzheimer's Disease

BACKGROUND: Recently, two large genome wide association studies in Alzheimer disease (AD) have identified variants in three different genes (CLU, PICALM and CR1) as being associated with the risk of developing AD. The strongest association was reported for an intronic single nucleotide polymorphism...

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Detalles Bibliográficos
Autores principales: Guerreiro, Rita J., Beck, John, Gibbs, J. Raphael, Santana, Isabel, Rossor, Martin N., Schott, Jonathan M., Nalls, Michael A., Ribeiro, Helena, Santiago, Beatriz, Fox, Nick C., Oliveira, Catarina, Collinge, John, Mead, Simon, Singleton, Andrew, Hardy, John
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831070/
https://www.ncbi.nlm.nih.gov/pubmed/20209083
http://dx.doi.org/10.1371/journal.pone.0009510