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Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability
RAD51, a key protein in the homologous recombinational DNA repair (HRR) pathway, is the major strand-transferase required for mitotic recombination. An important early step in HRR is the formation of single-stranded DNA (ss-DNA) coated by RPA (a ss-DNA-binding protein). Displacement of RPA by RAD51...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831301/ https://www.ncbi.nlm.nih.gov/pubmed/19942681 http://dx.doi.org/10.1093/nar/gkp1063 |