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Precise targeted integration by a chimaeric transposase zinc-finger fusion protein

Transposons of the Tc1/mariner family have been used to integrate foreign DNA stably into the genome of a large variety of different cell types and organisms. Integration is at TA dinucleotides located essentially at random throughout the genome, potentially leading to insertional mutagenesis, inapp...

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Detalles Bibliográficos
Autores principales: Feng, Xiaofeng, Bednarz, Amy L., Colloms, Sean D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831304/
https://www.ncbi.nlm.nih.gov/pubmed/19965773
http://dx.doi.org/10.1093/nar/gkp1068

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